top of page

Publications

  1. Acute decompensation of chronic hydrocephalus following elective abdominal surgery presenting as paroxysmal sympathetic hyperactivity. (2025). Veilleux C., Lang S., Hamilton M. JNS Case Lessons. Under Revision.

  2. Functional MRI reveals brain activation patters associated with optimization of spinal cord stimulation parameters in treating chronic pain. (2025). Vetkas A., Cheyuo C., Zemmar A., Santyr B., Chow C., Kashyap S., Yang B., Mojica M., Boutet A., Sarica C., Germann J., Lang S., Hajiabadi M., Yang A., Graham S., UludaÄŸ K., Bhatia A., Lozano A. Brain Stimulation. DOI: 10.1016/j.brs.2025.01.009

  3. Nazif B., Najafi F., Howard A., Lang S., Vila-Rodriguez F. (2025). DBS artifact during post-ictal generalized EEG suppression after ECT. The Journal of ECT. In press.

  4. Faran M., Pietramala D., Schmidt F., Polyhronopoulos N., Sandhu M., Dong J., Honey C., Lang S. (2025). Sex Disparity in Parkinson’s Disease Patients Undergoing Deep Brain Stimulation: A Single-Centre, Retrospective Cohort Study. Journal of Neurosurgery. In press

  5. Samuel, N., Germann, J., Yang, A., Sarica, C., Boutet, A., Vetkas, A., Santyr, B., Lang, S., Chicco, D., Lozano, A. (2024). Data-Driven Probabilistic Mapping of the Spatial and Molecular Landscape of Glioma. Preprint http://dx.doi.org/10.2139/ssrn.4967262.

  6. Ong, K., Schmidt F., Tosefsky K., Faran M., Sarica C., Honey C., Vila-Rodriguez F., Lang S. (2024). Non-motor effects of low-frequency deep brain stimulation of the subthalamic nucleus in Parkinson’s disease: a systematic review.  Stereotactic and Functional Neurosurgery. DOI: 10.1159/000540210

  7. Zima L., Harvin J., Deng H., Okonkwo D., Sieg E., Alhourani A., Jagid J., Krueger E., Taghavi S,. Nordham K., Lang S., Vetkas A., Kitagawa R., Lozano A., Conner C. (2024). Absence of July effect on trauma outcomes at the start of the academic medical calendar. Trauma. https://doi.org/10.1177/14604086231206308

  8. Sarica C, Conner C, Yamamoto K, Germann J, Yang A, Lannon MM, Samuel N, Colditz M, Santyr B, Chow C, Iorio-Morin C, Aguirre-Padilla DH, Lang S, Vetkas A, Cheyuo C, Loh A, Darmani G, Flouty O, Milano V, Paff M, Hodaie M, Kalia SK, Fasano A, Lozano AM. (2023). Trends and disparities in deep brain stimulation utilization in the United States: a nationwide inpatient sample analysis from 1993 to 2017. The Lancet Regional Health - Americas. https://doi.org/10.1016/j.lana.2023.100599

  9. Vetkas A., Boutet A., Samuel N., Germann J.,  Sarica C., Yamamoto K., Sartyr B., Cheyuo C., Lang S.,  Conner C., Ibrahim G., Valiante T., Kalia S., Lozano A. (2023). Successful MR-guided focused ultrasound treatment of tremor in patients with a skull density ratio below 0.4. Journal of Neurosurgery. https://doi.org/10.3171/2023.6.JNS23171

  10. Lang S., Momi D., Vetkas A., Santyr B., Yang A., Kalia S., Griffiths J., Lozano A. (2023). Computational modelling of whole brain dynamics: a systematic review of neurosurgical applications. Journal of Neurosurgery. https://doi.org/10.3171/2023.5.JNS23250

  11. Lang S., Vetkas A., Connor C., Lozano A., Kalia S. (2023). Predictors of future deep brain stimulation surgery in de novo Parkinson’s disease. Movement Disorders Clinical Practice. DOI: 10.1002/mdc3.13747

  12. Lang S., Dimond D., Isaacs A., Dronyk J., Vetkas A., Connor C., Germann J., Fasano A., Kalia S,. Lozano A., Hamilton M. (2023). Decreased cortical volume predicts response to temporary cerebrospinal fluid drainage in normal pressure hydrocephalus. Journal of Neurosurgery. DOI: 10.3171/2023.3.JNS222787.

  13. Vetkas A., Germann J., Boutet A., Samuel N., Sarica C., Yamamoto K., Sartyr B., Cheyuo C., Conner C., Lang S., Lozano A., Ibrahim G., Valiante T., Kongkham P., Kalia S. (2023). Laser interstitial thermal therapy for the treatment of insular lesions: a systematic review. Frontiers in Neurology. 10.3389/fneur.2022.1024075

  14. Danyluk H., Lang S., Monchi O., Sankar T. (2021). Pre-operative limbic system functional connectivity distinguishes responders from non-responders to surgical treatment for trigeminal neuralgia. Frontiers in Neurology. doi: 10.3389/fneur.2021.716500

  15. Yoon E., Ismail Z., Kathol I., Kibreab M., Hammer T., Lang S., Ramezani M., Auclair-Ouellet N., Sarna J., Martino D., Furtado S., Monchi O. (2021). Patterns of brain activity during a set-shifting task linked to mild behavioral impairment in Parkinson’s disease. Neuroimage: Clinical. https://doi.org/10.1016/j.nicl.2021.102590

  16. Lang S., Gan LS, McLennan C., Monchi O., Kirton A., Kelly J. (2020). Preoperative transcranial direct current stimulation in glioma patients: a proof of concept pilot study. Frontiers in Neurology. https://doi.org/10.3389/fneur.2020.593950

  17. Lang S., Gan LS., Yoon E.,  Hanganu A., Kibreab M., Auclair-Ouellet N., Cheetham J., Hammer T., Kathol I., Sarna J., Monchi O. (2020). Theta-burst stimulation for cognitive enhancement in Parkinson's disease with mild cognitive impairment: a randomized, double- blind, sham-controlled trial. Frontiers in Neurology. doi: 10.3389/fneur.2020.584374

  18. Lang S.*, Ryu A.*, Starreveld Y., Costello F. (2020). Good visual outcomes following pituitary tumor surgery are associated with increased visual cortex functional connectivity. Journal of Neuro-Ophthalmology. doi: 10.1097/WNO.0000000000001155

  19. Auclair-Ouellet N., Hanganu A., Mazerolle E., Lang S., Kibreab M., Ramezani M., Haffenden A., Hammer T., Cheetham J., Kathol I., Pike B., Sarna J., Martino D., Monchi O. (2020). Action fluency identifies different sex, age, global cognition, executive function and brain activation profile in non-demented patients with Parkinson’s disease. Journal of Neurology. https://doi.org/10.1007/s00415-020-10245-3

  20. Lang S., Ismail Z., Kibreab M., Kathol I., Sarna J., Monchi O. (2020). Common and unique neural connectivity at the interface of motor, behavioral, and cognitive symptoms in Parkinson’s disease: a commonality analysis. Human Brain Mapping. https://doi.org/10.1002/hbm.25084.

  21. Lang S., Yoon E., Kibreab M., Kathol I., Cheetham J., Hammer T., Sarna J., Ismail Z., Monchi O. (2020). Mild behavioral impairment in Parkinson’s disease is associated with altered corticostriatal connectivity. Neuroimage: Clinical. https://doi.org/10.1016/j.nicl.2020.102252

  22. Lang S.*, Gan LS.*, McLennan C., Monchi, O., Kelly J. (2020). Impact of peritumoral edema during tumor treatment field therapy: a computational modelling study. IEEE Transactions on Biomedical Engineering. doi: 10.1109/TBME.2020.2983653.

  23. Ben-Isreal, D., Casha, S., Jacobs, B., Lang, S., Ryu, A., de Lotbiniere-Basset, M., Cadotte, D. (2019). The impact of machine learning on patient care: a systematic review. Artificial Intelligence in Medicine. https://doi.org/10.1016/j.artmed.2019.101785

  24. Lang, S., Gan, LS., Alrazi, T., Monchi, O. (2019). High-definition transcranial alternating current stimulation, but not transcranial direct current stimulation, improves visual associative memory performance. Scientific Reports. 9(8562). https://doi.org/10.1038/s41598-019-44680-8.

  25. Lang S., Hanganu A., Gan LS., Kibreab M., Auclair-Ouellet N., Alrazi T., Ramezani M., Cheetham J., Hammer T., Kathol I., Sarna J., Monchi O. (2019). Network basis of the dysexecutive and posterior cortical cognitive profiles in Parkinson’s Disease. Movement Disorders. DOI: 10.1002/mds.27674

  26. Ramasubbu R., Lang S., & Kiss ZHT (2018) Dosing of electrical parameters in deep brain stimulation (DBS) for intractable depression: A review of clinical studies. Frontiers in Psychiatry. 9:302. doi: 10.3389/fpsyt.2018.00302

  27. Opoku-Darko M., Lang S., Artindale J., Cairncross G., Sevick R., Kelly J. (2018) Surgical management of incidentally discovered diffusely infiltrating glioma. Journal of Neurosurgery. DOI: 10.3171/2017.3.JNS17159.  

  28. Ciechanski, P., Cheng, A., Lopushinsky, S., Hecker, K., Gan, L., Lang, S., Sutherland, G., Kirton, A. (2017). Effects of transcranial direct-current stimulation on neurosurgical skill acquisition: a randomized controlled trial. World Neurosurgery. https://doi.org/10.1016/j.wneu.2017.08.123

  29. Lang S., Gaxiola-Valdez I., Opoku-Darko M., Partlo L., Goodyear B., Kelly J., Federico P. (2017). Resting state functional connectivity in the fronto-parietal network: an indicator for pre-operative cognitive function and cognitive outcome following surgery in patients with diffuse glioma. World Neurosurgery. DOI: 10.1016/j.wneu.2017.05.149

  30. Lang S., Cadieux M., Opoku-Darko M., Gaxiola-Valdez I., Partlo L., Goodyear B., Federico P., Kelly J. (2017). Assessment of cognitive, emotional, and motor domains in patients with diffuse glioma utilizing the NIH toolbox battery. World Neurosurgery. DOI: 10.1016/j.wneu.2016.12.061

  31. Lang S. (2016). Cognitive eloquence in neurosurgery: Insight from graph theoretical analysis of complex brain networks. Medical Hypotheses. http://dx.doi.org/10.1016/j.mehy.2016.11.010

  32. Lang S., Assis Z, Wong JH, Morrish, WE, Mitha AP. (2016). Rapid delayed growth of ruptured supraclinoid blister aneurysm after successful flow-diverting stent treatment. Journal of Neurointerventional Surgery. DOI: 10.1136/neurintsurg-2016-012506.rep

  33. Lang S., Duncan N, Northoff G. (2014). Resting state fMRI: review of neurosurgical applications. Neurosurgery; 74(5): 453-465

  34. Hayes, D., Duncan, N., Wiebking, C., Tiret, B., Pietruska, K., Lyttleton, O., Qin, P., Gagnon, J., Lang, S., Gravel, P., Verhaeghe, J., Kostikov, A., Schirrmacher, R., Reader, A., Doyon, J., Rainville, P., Northoff, G. (2013). GABAA receptors predict aversion-related brain responses: An fMRI-PET investigation in healthy humans. Neuropsychopharmacology; 38(8):1438-1450

  35. Lang, S. (2012). Deep brain stimulation for neuropsychiatric disorders: a revolution in treatment or a return to the dark ages? University of Ottawa Journal of Medicine; 2(1): 15-18

  36. Limebeer, C., Vemuri, V., Bedard, H., Lang, S., Ossenkopp, K., Makriyannis, A., Parker, L. (2010). Inverse agonism of cannabinoid CB1 receptors potentiates LiCl-induced nausea in the conditioned gaping model in rats. British Journal of Pharmacology;161: 336-349  

  37. Manwell, L., Satvat, E., Lang, S., Allen, C., Leri, F., Parker, L. (2009). FAAH inhibitor, URB 597, promotes extinction and CB1 antagonist, SR 141716, inhibits extinction of conditioned aversion produced by naloxone-precipitated morphine withdrawal, but not extinction of conditioned preference produced by morphine in rats. Pharmacology, Biochemistry, and Behavior; 94(1): 154-162

Contact Information

8124-2775 Laurel Street, Vancouver

Department of Surgery

Division of Neurosurgery

University of British Columbia

If you are a student or post-doc interested in research please email stefan.lang@vch.ca with your CV and a paragraph on your interests.

If you are interested in clinical care, please have your neurologist or family physician fax a referral. 

Phone: 604-875-5540

Fax: 604-630-7086

  • Twitter
bottom of page